Inés Magdalena Martinez Alfonzo
Inés Magdalena Martinez Alfonzo

Dra. Inés Magdalena Martinez Alfonzo

Adjunta Hematología y Hemoterapia. Departamento de Coagulación
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Datos del profesional

Experience

  • 2020-Present. Hematology Attending. Laboratory of Hemostasis and outpatient thrombosis and hemostasis. Jiménez Díaz Foundation.
  • 2023-present. Assistant Hematology. Outpatient gestational pathology. Jiménez Díaz Foundation.
  • 2022-Present. Assistant Hematology. Hematology outpatient clinic (private). Jiménez Díaz Foundation.
  • 2022-present. Hematology Assistant. Outpatient Anticoagulate treatment management. Jimenez Diaz Foundation.
  • 2016 - 2020. MIR Hematology and Hemotherapy / Fundación Jiménez Díaz.

Degree

  • Degree in Medicine and Surgery, Universidad Central de Venezuela (2013).
  • Specialist in Hematology and Hemotherapy (2016-2020).

Techniques

Hemostasis laboratory techniques:

  • Basic and special coagulation tests (PT, aPTT, fibrinogen, D-dimer, factors, thrombophilia study, lupus anticoagulant) using ACL TOP and AcuStar.
  • Determination of anticoagulant levels (antiXa, apixaban, edoxaban, rivaroxaban, dabigatran).
  • Platelet function study with PFA-100, optical aggregometry (Born), Multiplate and VerifyNow.
  • Complete determination of von Willebrand factor, including multimer analysis.
  • Technical and clinical validation of results.

Research and teaching

Research:

  • Doctoral thesis. "Search for new predictive models of venous thrombosis in patients with multiple myeloma using artificial intelligence algorithm".
  • Registry of cardioembolic prophylaxis in cancer patients undergoing oncospecific treatment (PROCECAN-2021).

Teaching:

  • Teaching collaborator Alfonso X University (UAX)

Publications

1. Significant attenuation of fully automated thrombin generation in newly diagnosed multiple myeloma patients after induction therapy. J Thromb Thrombolysis. 2025 Mar;58(3):467-480.
2. Can the total thrombus-formation analysis system predict bleeding risk in individuals with VWF levels between 30 and 50 IU/dL? Thromb Res. 2025 Mar;247:109260.
3. Enhanced thrombin generation detected with ST-Genesia analyzer in patients with newly diagnosed multiple myeloma. J Thromb Thrombolysis. 2023 Apr;55(3):464-473.
4. Flow Cytometry and Molecular Techniques Could Complement Morphological Detection of Leukemic Infiltration in Ascitic Fluids: A Case Report. Medicina (Kaunas). 2022 Feb 10;58(2):264.
5. A journey through anticoagulant therapies in the treatment of left ventricular thrombus in post-COVID-19 heparin-induced thrombocytopenia: a case report. Hematology. 2022 Dec;27(1):318-321.
6. Incidence and clinical profile of venous thromboembolism in hospitalized COVID-19 patients from Madrid region. Thromb Res. 2021 Jul;203:93-100.
7. Development and validation of a predictive model of in-hospital mortality in COVID-19 patients. PLoS One. 2021 Mar 4;16(3):e0247676.
8. A novel hemocompatible core@shell nanosystem for selective targeting and apoptosis induction in cancer cells.
9. Book or scientific monograph. 2021. COVID-19 and thrombotic risk. Particularities in pregnant women. Update on thrombotic risk in women. Esmon Publicidad, S.A.. 1.

Communications and Presentations

1. Scientific Symposium: Advancing thrombotic risk models in myeloma and lymphoma. LXVI National Meeting of the SEHH and XL National Congress of the SETH.
2. Oral communication: Evaluation of the TORADI-HIT automated model in patients with suspected heparin-induced thrombopenia. LXV National Meeting of the SEHH XXXIX National Congress of the SETH.
3. Oral communication: Validation of the feasibility of performing automated thrombin generation test in a multicenter and decentralized manner. LXV National Meeting of the SEHH XXXIX National Congress of the SETH.
4. Differences in thrombin generation in patients with newly diagnosed multiple myeloma and assessment of the role of thromboprophylaxis with heparin. XXXVIII National Congress of the Spanish Society of Thrombosis and Hemostasis.
5. Oral communication: Venous thromboembolic disease in hospitalized COVID-19 patients with hematological malignancies. Multicenter study in the community of Madrid. XXXVIII National Congress of the Spanish Society of Thrombosis and Hemostasis.
6. Oral communication: Machine learning versus logistic regression in the generation of predictive models of venous thrombosis in patients with multiple myeloma. Multicenter study. XXXVIII National Congress of the Spanish Society of Thrombosis and Hemostasis.
7. Oral communication: NEW APPROXIMATION FOR THE PREDICTION OF VENOUS TROMBOEMBOLISM IN MULTIPLE MYELOMA BY USING MACHINE LEARNING ALGORITHMS. LXII National Congress of the SEHH and XXXVI National Congress of the SETH.
8. Poster: EFFECT OF THE USE OF GRANULOCYTIC COLONY STIMULATING FACTOR AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION. 46th European Society for Blood and Marrow Transplantation.
9. RISK OF DEVELOPING VENOUS THROMBOEMBOLISM IN MULTIPLE MYLOMA; BASED ON CURRENT VTE RISK ASSESSMENT MODELS: IMPEDE VTE SCORE & IMWG GUIDELINES. 17th International Myeloma Worshop.
10. INMUNE RECONSTITUTION OF LYMPHOCYTE SUBSETS AFTER ALLOGENIC STEM CELL TRANSPLANT AND VACCINATION. 45th European Society for Blood and Marrow Transplantation
11. AUTOLOGOUS TRANSPLANTATION IN PATIENTS OVER 65 YEARS OLD. International Society of Geriatric Oncology.

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