Experience
Specialist in Medical Oncology (HU La Paz), 2012
Clinical Fellow in the Mesenchymal Tumors Unit from Istituto Nazionale dei Tumori (Milan)- 2013-2015
Specialist in Sarcoma Unit at HU Virgen del Rocío (2015-2020)
Degree
DEGREE IN MEDICINE (2007), SPECIALIST IN MEDICAL ONCOLOGY (2012)
Techniques
Treatment of patients with soft tissue sarcomas, bone sarcomas, and GIST. Systemic treatment, targeted therapies, clinical trials
Research and teaching
Principal Investigator/Sub-Investigator in over 40 clinical trials on soft tissue sarcomas, bone sarcomas, and GIST.
Collaborating researcher in more than 20 research projects, including translational research and 2 European projects (Horizon 2020 and Horizon Europe).
Principal Investigator in 4 translational research projects.
Teaching Collaborator at the Autonomous University of Madrid and Alfonso X el Sabio University.
Lecturer in the Master’s Program on Musculoskeletal Tumors at the European University of Madrid.
Teaching Collaborator at the University of Seville.
Publications
Author of more than 90 indexed publications:
1 J Martin-Broto; A Redondo; DS Moura; et al; N Hindi. 2022. A phase II trial of weekly nab-paclitaxel for progressive and symptomatic desmoid tumors. Nat Commun. 13-1, pp.6278. https://doi.org/10.1038/s41467-022-33975-6.
2 J Martin-Broto; R Diaz-Betveritge; DS Moura; et al; N Hindi. 2025. Phase Ib Study for the Combination of Doxorubicin, Dacarbazine, and Nivolumab as the Upfront Treatment in Patients With Advanced Leiomyosarcoma: A Study by the Spanish Sarcoma Group (GEIS). J Clin Oncol. 43-3, pp.297-307.
3. N Hindi; A Razak; E Rosenbaum; et al. 2023. Efficacy of immune checkpoint inhibitors in alveolar soft-part sarcoma: results from a retrospective worldwide registry. ESMO Open. 8-6, pp.102045.
4. Martin Broto J; Martinez J; Moura DS; et al; (19/19) Hindi N. 2023. Phase II trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/CDJB2A. Signal transduction and targeted therapy. 8-1. https://doi.org/10.1038/s41392-023-01661-8
5. Martin Broto J; Valverde C; Hindi N; et al. 2023. REGISTRI: Regorafenib in first-line of KIT/PDGFRA wild type metastatic GIST: a collaborative Spanish (GEIS), Italian (ISG) and French Sarcoma Group (FSG) phase II trial. Mol Cancer. https://doi.org/10.1186/s12943-023-01832-9.
6. Nadia Hindi; Nadia Laack; Kevin Hong; Peter Hohenberger. 2023. Local Therapies for Metastatic Sarcoma: Why, When, and How?. Am Soc Clin Oncol Educ Book. 43, pp.e390554.
7. Roberta Sanfilippo; Nadia Hindi; Josefina Cruz Jurado; et al. 2023. Effectiveness and Safety of Trabectedin and Radiotherapy for Patients With Myxoid Liposarcoma: A Nonrandomized Clinical Trial. JAMA Oncology. 9-5, pp.656-663.
8. N Hindi; J Carrillo-Garcia; E Blanco-Alcaina; et al; J Martin-Broto. 2023. Platinum-Based Regimens Are Active in Advanced Pediatric-Type Rhabdomyosarcoma in Adults and Depending on HMGB1 Expression. Int J Mol Sci. 24-1, pp.856. https://doi.org/10.3390/ijms24010856
9. JY Blay; N Hindi; J Bollard; et al. 2022. SELNET clinical practice guidelines for soft tissue sarcoma and GIST. Cancer Treat Rev. 102, pp.102312.
10. N Hindi; I Carrasco-Garcia; A Sanchez-Camacho; et al; J Martin-Broto. 2020. Trabectedin Plus Radiotherapy for Advanced Soft-Tissue Sarcoma: Experience in Forty Patients Treated at a Sarcoma Reference Center.Cancers (Basel). 12-12, pp.3740.
11. J Martin-Broto; N Hindi; G Grignani; et al; JA Lopez-Martin. 2020. Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial. Journal for Immunotherapy of Cancer. 8-2, pp.e001561.
12. Martin-Broto J; Hindi N; Aguiar S Jr; et al; Blay JY.2020. Sarcoma European and Latin American Network (SELNET) Recommendations on Prioritization in Sarcoma Care During the COVID-19 Pandemic. The Oncologist.
13. Martin-Broto J; Hindi N; Lopez-Pousa A; et al; Moura DS. 2020. Assessment of Safety and Efficacy of Combined Trabectedin and Low-Dose Radiotherapy for Patients With Metastatic Soft-Tissue
Sarcomas: A Nonrandomized Phase 1/2 Clinical Trial. JAMA oncology.
. https://doi.org/10.1001/jamaoncol.2019.6584
14. Fucà G; Hindi N; Ray-Coquard I; et al; Sanfilippo R. 2019. Treatment Outcomes and Sensitivity to Hormone Therapy of Aggressive Angiomyxoma: A Multicenter, International, Retrospective Study.The oncologist. 24(7), pp.e536-e541. ISSN 1083-7159. https://doi.org/10.1634/theoncologist.2018-0338
15. Martin-Broto J; Hindi N; Cruz J; et al; Lopez-Pousa A. 2019. Relevance of Reference Centers in Sarcoma Care and Quality Item Evaluation: Results from the Prospective Registry of the Spanish Group for Research in Sarcoma (GEIS).The oncologist. 24(6), pp.e338-e346. ISSN 1083-7159. https://doi.org/10.1634/theoncologist.2018-0121
16. Martin-Broto J; Moura DS; Hindi N. 2019. Pazopanib in the treatment of advanced solitary fibrous tumour - Authors' reply.The Lancet. Oncology. 20(3), pp.e128. ISSN 1470-2045. https://doi.org/10.1016/S1470-2045(19)30080-4
17. Gronchi A; Hindi N; Cruz J; et al; Martin-Broto J. 2019. Trabectedin and RAdiotherapy in Soft Tissue Sarcoma (TRASTS): Results of a Phase I Study in Myxoid Liposarcoma from Spanish (GEIS),
Italian (ISG), French (FSG) Sarcoma Groups.EClinicalMedicine. 9, pp.35-43. ISSN 2589-5370. https://doi.org/10.1016/j.eclinm.2019.03.007
18. Hindi N; Casali PG; Morosi C; et al; Stacchiotti S. 2015. Imatinib in advanced chordoma: A retrospective case series analysis.European journal of cancer (Oxford, England : 1990).
Communications and Presentations
More than 100 congress communications in national and international conferences.
Awards and certifications
Clinical Research Grant from the Sociedad Española de Oncología Médica (SEOM)- 2012
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