Dr. Víctor Domínguez Prieto

• - 2018 – 2023: Resident physician in General and Digestive System Surgery – Fundación Jiménez Díaz University Hospital
• - 2023 – currently: Specialist in General and Digestive System Surgery. Hepatobiliopancreatic Surgery, Peritoneal Oncological Surgery and Sarcomas Unit – Fundación Jiménez Díaz University Hospital

• - Hepatobiliary surgery: Major and minor liver resections, bile duct resection, biliodigestive derivation, cholecystectomy, bile duct exploration...
• - Pancreatic surgery: Cephalic pancreatoduodenectomy, distal pancreatectomy, enucleation of pancreatic tumors, splenectomy...
• - Peritoneal cancer surgery: Cytoreduction surgery, HIPEC, PIPAC
• - Retroperitoneal sarcoma surgery
• - Abdominal wall: Open and minimally invasive surgery of inguinal hernia and diastasis
• - Approaches: Open, laparoscopic and robotic-assisted

Main research lines:

• - Biomarkers in liquid biopsy in patients with colorectal cancer: Hypermethylation of SEPTIN9 gene as a biomarker for response assessment and follow-up in patients with locally advanced rectal cancer
• - Chemical scalpel: Local administration of collagenase for dissection of scirrhus tumors and removal of postoperative adhesions (Proyectos de Desarrollo Tecnológico en Salud 2022, Instituto de Salud Carlos III)
• - GECOP-MMC clinical trial: Phase IV randomized clinical trial to evaluate the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) with mytomicin-C after complete surgical cytoreduction in patients with colon cancer peritoneal metastases

Teaching:

• - Associate Professor, Degree in Medicine – Universidad Alfonso X
• - Teaching Clinical Collaborator, Degree in Medicine – Universidad Autónoma de Madrid

- López-Rojo I, Olmedillas-López S, Villarejo Campos P, Domínguez Prieto V, Barambio Buendía J, Cortés Guiral D, García-Arranz M, García-Olmo D. Liquid biopsy in peritoneal fluid and plasma as a prognostic factor in advanced colorectal and appendiceal tumors after complete cytoreduction and hyperthermic intraperitoneal chemotherapy. Ther Adv Med Oncol. 2020 Dec 18;12:1758835920981351. doi: 10.1177/1758835920981351
- Domínguez-Prieto V, Barambio-Buendía J, Vizarreta-Figueroa AT, Meliga C, Guijo-Castellano I, Villarejo-Campos P. Value of three-dimensional reconstruction for non-invasive estimation of PCI in patients with peritoneal carcinomatosis of colorectal origin: A proof of concept. Cir Esp (Engl Ed). 2024 Jan;102(1):56-58. doi: 10.1016/j.cireng.2023.02.003
- Domínguez-Prieto V, Qian S, Villarejo-Campos P, Meliga C, González-Soares S, Guijo Castellano I, Jiménez-Galanes S, García-Arranz M, Guadalajara H, García-Olmo D. Understanding CAR T cell therapy and its role in ovarian cancer and peritoneal carcinomatosis from ovarian cancer. Front Oncol. 2023 May 18;13:1104547. doi: 10.3389/fonc.2023.1104547
- Villarejo-Campos P, García-Arranz M, Qian S, Jiménez de Los Galanes S, Domínguez-Prieto V, Vélez-Pinto JF, Guijo Castellano I, Jiménez-Fuertes M, Guadalajara H, García-Olmo D. Under the Hood: Understanding the Features of Mucin in Pseudomyxoma Peritonei. J Clin Med. 2023 Jun 12;12(12):4007. doi: 10.3390/jcm12124007
- Domínguez-Prieto V, León-Arellano M, Olivera-Salazar R, Vega-Clemente L, Caramés C, Ruiz-Hispán E, Fuentes-Mateos R, Rosero-Rodríguez D, Guadalajara H, García-Arranz M, García-Olmo D. Pre-Treatment SEPTIN9 Gene Methylation Ratio Predicts Tumor Response to Total Neoadjuvant Therapy in Patients with Locally Advanced Rectal Cancer. Cancers (Basel). 2025 Mar 13;17(6):965. doi: 10.3390/cancers17060965
- Sánchez MM, Domínguez-Prieto V, Qian Zhang S, Quiceno Arias HD, Álvarez Álvarez MB, Fuertes MJ, Meliga C, Jiménez-Galanes S, Labajo HG, Olmo DG, Campos PV. Inflammatory Fibroid Polyp (Vanek's Tumor): A Retrospective Multicentric Analysis of 67 Cases. Cancers (Basel). 2025 Apr 2;17(7):1209. doi: 10.3390/cancers17071209